Phenobarbital influence on neuromuscular block produced by rocuronium in rats Influência do fenobarbital no bloqueio neuromuscular produzido pelo rocurônio em ratos

Phenobarbital influence on neuromuscular block produced by rocuronium in rats Influência do fenobarbital no bloqueio neuromuscular produzido pelo rocurônio em ratos

PURPOSE: To evaluate in vitro and in vivo neuromuscular blockade produced by rocuronium in rats treated with Phenobarbital and to determine cytochrome P450 and cytochrome b5 concentrations in hepatic microsomes. METHODS: Thirty rats were included in the study and distributed into 6 groups of 5 anima...

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Bibliographic Details
Main Authors: Angélica de Fátima de Assunção Braga, Caroline Coutinho de Barcelos, Franklin Sarmento da Silva Braga, Samanta Cristina Antoniassi Fernandes, Yoko Oshima Franco, Mario Mantovani, Léa Rodrigues Simioni
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2008-08-01
Series:Acta Cirurgica Brasileira
Subjects:
Fenobarbital
Bloqueadores Neuromusculares
Ratos
Phenobarbital
Neuromuscular Blocking Agents
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000400008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000400008

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