Age-Related Immune Profile of the T Cell Receptor Repertoire, Thymic Recent Output Function, and miRNAs

Background. T cell immunity plays a central role in the body’s defense system, including maintaining homeostasis and preventing tumorigenesis and viral infection. Immune system functions degenerate with age, leading to immune senescence. Physiologically, immune senescence is characterized by a decre...

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Bibliographic Details
Main Authors: Yan Xu, Ling Xu, Cunte Chen, Yikai Zhang, Chengwu Zeng, Zhenyi Jin, Shaohua Chen, Bo Li, Xianfeng Zha, Zhinan Yin, Yangqiu Li
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/5910823