Conjugation of Steroidal and Non – Steroidal Anti- Inflammatory Drugs as Possible Mutual Prodrug
Prednisolone (SAID) was conjugated with ibuprofen (NSAID) through an amino acid (glycine) as a spacer arm to synthesize the following compound: Prednisolone – glycine – ibuprofen. The method employed consists of converting the carboxylic acid function of (R,S) – ibuprofen – glycin...
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Format: | Article |
Language: | English |
Published: |
College of Pharmacy University of Baghdad
2017-04-01
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Series: | Iraqi Journal of Pharmaceutical Sciences |
Online Access: | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/630 |