Detection of Mycobacterium tuberculosis-derived DNA in circulating cell-free DNA from a patient with disseminated infection using digital PCR

Detection of Mycobacterium tuberculosis-derived DNA in circulating cell-free DNA from a patient with disseminated infection using digital PCR

Mycobacterium tuberculosis (MTB) can disseminate to extrapulmonary organs, particularly in severely immunosuppressed patients. Confirmation of active MTB infection is often difficult in subjects with a contraindication for invasive procedures. A case of disseminated MTB infection after hematopoietic...

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Bibliographic Details
Main Authors: Masaki Yamamoto, Ryota Ushio, Hiroki Watanabe, Takayoshi Tachibana, Masatsugu Tanaka, Tomoyuki Yokose, Jun Tsukiji, Hideaki Nakajima, Takeshi Kaneko
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:International Journal of Infectious Diseases
Subjects:
Mycobacterium tuberculosis
Extrapulmonary infection
Digital PCR
Circulating cell-free DNA
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217303004

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http://www.sciencedirect.com/science/article/pii/S1201971217303004

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