Comprehensive Analysis of APA Events and Their Association With Tumor Microenvironment in Lung Adenocarcinoma

BackgroundAlternative polyadenylation (APA) is a pervasive posttranscriptional mechanism regulating gene expression. However, the specific dysregulation of APA events and its potential biological or clinical significance in lung adenocarcinoma (LUAD) remain unclear.MethodsHere, we collected RNA-Seq...

Full description

Bibliographic Details
Main Authors: Yuchu Zhang, Libing Shen, Qili Shi, Guofang Zhao, Fajiu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.645360/full