Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis

Abstract Development of advanced hepatic fibrosis in HFE Hemochromatosis (HH) is influenced by hepatic iron concentration (HIC) and age. In patients with HH, it is important to assess the likelihood of cirrhosis and thus the need for confirmatory liver biopsy. Therapeutic phlebotomy also provides an...

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Bibliographic Details
Main Authors: Justin Chin, Lawrie W. Powell, Louise E. Ramm, Oyekoya T. Ayonrinde, Grant A. Ramm, John K. Olynyk
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-56732-0