Cytotoxic Activity of the Histone Deacetylase 3-Selective Inhibitor Pojamide on MDA-MB-231 Triple-Negative Breast Cancer Cells

Cytotoxic Activity of the Histone Deacetylase 3-Selective Inhibitor Pojamide on MDA-MB-231 Triple-Negative Breast Cancer Cells

We examined the effects of the ferrocene-based histone deacetylase-3 inhibitor Pojamide (<i>N</i><sup>1</sup>-(2-aminophenyl)-<i>N</i><sup>8</sup>-ferrocenyloctanediamide) and its two derivatives <i>N</i><sup>1</sup>-(2-aminophe...

Full description

Bibliographic Details
Main Authors: Claudio Luparello, Dalia Maria Lucia Asaro, Ilenia Cruciata, Storm Hassell-Hart, Supojjanee Sansook, John Spencer, Fabio Caradonna
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
histone deacetylase inhibitor
breast cancer cells
cell viability
cell cycle
apoptosis
autophagy
reactive oxygen species
mitochondrial transmembrane potential
Online Access:https://www.mdpi.com/1422-0067/20/4/804

Internet

https://www.mdpi.com/1422-0067/20/4/804

Similar Items