Signatures of Dermal Fibroblasts from RDEB Pediatric Patients

Signatures of Dermal Fibroblasts from RDEB Pediatric Patients

The recessive form of dystrophic epidermolysis bullosa (RDEB) is a debilitating disease caused by impairments in the junctions of the dermis and the basement membrane of the epidermis. Mutations in the COL7A1 gene induce multiple abnormalities, including chronic inflammation and profibrotic changes...

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Bibliographic Details
Main Authors: Arkadii K. Beilin, Nadezhda A. Evtushenko, Daniil K. Lukyanov, Nikolay N. Murashkin, Eduard T. Ambarchian, Alexander A. Pushkov, Kirill V. Savostyanov, Andrey P. Fisenko, Olga S. Rogovaya, Andrey V. Vasiliev, Ekaterina A. Vorotelyak, Nadya G. Gurskaya
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
epidermolysis bullosa
RDEB
COL7A1
disease mutation
splicing
dermal fibroblast
Online Access:https://www.mdpi.com/1422-0067/22/4/1792

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https://www.mdpi.com/1422-0067/22/4/1792

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