Deletion of GCN2 affects whole body and tissue response to asparaginase
Asparaginase (ASNase) treatment results in the synthesis of some factors such as activating-transcription-factor-4 (ATF4). The eIF2-ATF4 pathway is essential for cell survival during amino acid starvation conditions. This requires the eukaryotic-initiation-factor-2 (eIF2) kinase called general contr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Veterinary Medicine
2017-12-01
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| Series: | Al-Qadisiyah Journal of Veterinary Medicine Sciences |
| Online Access: | http://www.qu.edu.iq/journalvm/index.php/vm_journal/article/view/459 |