High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

<p>Abstract</p> <p>Background</p> <p>Bcl-2 promotes cell survival by inhibiting adapters needed for the activation and cleavage of caspases thus blocking the proteolytic cascade that ultimately dismantles the cell. Bcl-2 has been investigated as a prognostic factor in n...

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Main Authors: Detterbeck Frank, Gettinger Scott, Boffa Daniel, Tanoue Lynn, Frangia Konstantina, Panagopoulos Nikolaos, Liceaga Camil, Gopinath Arun, Tzelepi Vassiliki, Zolota Vassiliki, Lowery Frank J, Anagnostou Valsamo K, Homer Robert J, Dougenis Dimitrios, Rimm David L, Syrigos Konstantinos N
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/186

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http://www.biomedcentral.com/1471-2407/10/186

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