Binding characteristics of a panel of monoclonal antibodies against the ligand binding domain of the human LDLr
To obtain a panel of monoclonal antibodies (MAbs) to study the folding and conformation of the low density lipoprotein receptor (LDLr), we have generated hybridomas from LDLr-deficient mice that had been immunized with the extracellular domain of the human LDLr. The 12 MAbs were specific for the lig...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520331837 |