Binding characteristics of a panel of monoclonal antibodies against the ligand binding domain of the human LDLr

To obtain a panel of monoclonal antibodies (MAbs) to study the folding and conformation of the low density lipoprotein receptor (LDLr), we have generated hybridomas from LDLr-deficient mice that had been immunized with the extracellular domain of the human LDLr. The 12 MAbs were specific for the lig...

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Bibliographic Details
Main Authors: Anh T. Nguyen, Tomoko Hirama, Vinita Chauhan, Roger MacKenzie, Ross Milne
Format: Article
Language:English
Published: Elsevier 2006-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331837