Safety and efficacy assessment of two new leprosy skin test antigens: randomized double blind clinical study.

Safety and efficacy assessment of two new leprosy skin test antigens: randomized double blind clinical study.

New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in human trials.A Phase I safety trial was first conducted in a...

Full description

Bibliographic Details
Main Authors: Becky L Rivoire, Nathan A Groathouse, Stephen TerLouw, Kapil Dev Neupane, Chaman Ranjit, Bishwa Raj Sapkota, Saraswoti Khadge, Chhatra B Kunwar, Murdo Macdonald, Rachel Hawksworth, Min B Thapa, Deanna A Hagge, Melinda Tibbals, Carol Smith, Tina Dube, Dewei She, Mark Wolff, Eric Zhou, Mamodikoe Makhene, Robin Mason, Christine Sizemore, Patrick J Brennan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4038488?pdf=render

Internet

http://europepmc.org/articles/PMC4038488?pdf=render

Similar Items