The improvement of treatment efficacy of gastropathy associated with the use of nonsteroidal anti-inflammatory drugs in Helicobacter pylori-negative patients with osteoarthritis

Among the more common side effects of osteoarthritis treatment are NSAID-gastropathy and NSAID-enteropathy. NSAIDs can cause direct injury to colon tissue and also impair synthesis of prostaglandins, reduce mucosal integrity, increase permeability and promote an influx of bacteria and toxins. Altera...

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Bibliographic Details
Main Authors: Antonenko Antonina V., Beregova Tetyana V.
Format: Article
Language:English
Published: Sciendo 2014-12-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:https://doi.org/10.1515/cipms-2015-0023