Uric acid shown to contribute to increased oxidative stress level independent of xanthine oxidoreductase activity in MedCity21 health examination registry

Abstract Uric acid has both antioxidant and pro-oxidant properties in vitro by scavenging and production of reactive oxygen species (ROS). This cross-sectional study examined whether uric acid possesses effects on oxidative stress under physiological conditions independent of xanthine oxidoreductase...

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Bibliographic Details
Main Authors: Masafumi Kurajoh, Shinya Fukumoto, Shio Yoshida, Seigo Akari, Takayo Murase, Takashi Nakamura, Haruka Ishii, Hisako Yoshida, Yuki Nagata, Tomoaki Morioka, Katsuhito Mori, Yasuo Imanishi, Kazuto Hirata, Masanori Emoto
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86962-0