In silico identification of drug target pathways in breast cancer subtypes using pathway cross-talk inhibition

In silico identification of drug target pathways in breast cancer subtypes using pathway cross-talk inhibition

Abstract Background Despite great development in genome and proteome high-throughput methods, treatment failure is a critical point in the management of most solid cancers, including breast cancer (BC). Multiple alternative mechanisms upon drug treatment are involved to offset therapeutic effects, e...

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Bibliographic Details
Main Authors: Claudia Cava, Gloria Bertoli, Isabella Castiglioni
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Translational Medicine
Subjects:
Monte Carlo cross-validation
Pathway cross-talk inhibition
Breast cancer
Drugs
Classification
Subtypes
Online Access:http://link.springer.com/article/10.1186/s12967-018-1535-2

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http://link.springer.com/article/10.1186/s12967-018-1535-2

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