Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection.

Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection.

Heme crystallization as hemozoin represents the dominant mechanism of heme disposal in blood feeding triatomine insect vectors of the Chagas disease. The absence of drugs or vaccine for the Chagas disease causative agent, the parasite Trypanosoma cruzi, makes the control of vector population the bes...

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Bibliographic Details
Main Authors: Caroline M Ferreira, Renata Stiebler, Francis M Saraiva, Guilherme C Lechuga, Ana Beatriz Walter-Nuno, Saulo C Bourguignon, Marcelo S Gonzalez, Patrícia Azambuja, Ana Caroline P Gandara, Rubem F S Menna-Barreto, Gabriela O Paiva-Silva, Marcia C Paes, Marcus F Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6084092?pdf=render

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http://europepmc.org/articles/PMC6084092?pdf=render

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