Anti-colorectal cancer effects of anti-p21Ras scFv delivered by the recombinant adenovirus KGHV500 and cytokine-induced killer cells

Anti-colorectal cancer effects of anti-p21Ras scFv delivered by the recombinant adenovirus KGHV500 and cytokine-induced killer cells

Abstract Background Colorectal cancer (CRC) is the most common type of gastrointestinal cancer. CRC gene therapy mediated by adenovirus holds great promise for the treatment of malignancies. However, intravenous delivery of adenovirus exhibits limited anti-tumor activity in vivo when used alone. Met...

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Bibliographic Details
Main Authors: Fang-Rui Liu, Shuang Bai, Qiang Feng, Xin-Yan Pan, Shu-Ling Song, Hong Fang, Jing Cui, Ju-Lun Yang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
Ras
Colorectal cancer
Adenovirus
CIK
scFv
Online Access:http://link.springer.com/article/10.1186/s12885-018-4989-y

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http://link.springer.com/article/10.1186/s12885-018-4989-y

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