Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization.

<h4>Background</h4>Joint inflammation is the common feature underlying juvenile idiopathic arthritis (JIA). Clinicians recognize patterns of joint involvement currently not part of the International League of Associations for Rheumatology (ILAR) classification. Using unsupervised machine...

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Bibliographic Details
Main Authors: Simon W M Eng, Florence A Aeschlimann, Mira van Veenendaal, Roberta A Berard, Alan M Rosenberg, Quaid Morris, Rae S M Yeung, ReACCh-Out Research Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002750