AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

Pantazopoulou et al. find that AGO2 resides in open-ended tunneling nanotubes and close-ended cytokinetic bridges. At the latter location, AGO2 colocalizes with cell division components and the authors show that AGO2 depletion impairs cell division fidelity.

Bibliographic Details
Main Authors: Vasiliki I. Pantazopoulou, Anastasios D. Delis, Stella Georgiou, Stamatis N. Pagakis, Vicky Filippa, Eleni Dragona, Ismini Kloukina, Elias Chatzitheodoridis, Jonel Trebicka, Athanassios D. Velentzas, Maja Thiele, Sarantis Gagos, Dimitris Thanos, Sofia Tseleni-Balafouta, Dimitrios J. Stravopodis, Ema Anastasiadou
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02130-0

Internet

https://doi.org/10.1038/s42003-021-02130-0

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