Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines.

Human tumor cell lines form the basis of the majority of present day laboratory cancer research. These models are vital to studying the molecular biology of tumors and preclinical testing of new therapies. When compared to traditional adherent cell lines, suspension cell lines recapitulate the genet...

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Main Authors: Zev A Binder, Kelli M Wilson, Vafi Salmasi, Brent A Orr, Charles G Eberhart, I-Mei Siu, Michael Lim, Jon D Weingart, Alfredo Quinones-Hinojosa, Chetan Bettegowda, Amin B Kassam, Alessandro Olivi, Henry Brem, Gregory J Riggins, Gary L Gallia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4814135?pdf=render