Programming Hippocampal Neural Stem/Progenitor Cells into Oligodendrocytes Enhances Remyelination in the Adult Brain after Injury

Demyelinating diseases are characterized by a loss of oligodendrocytes leading to axonal degeneration and impaired brain function. Current strategies used for the treatment of demyelinating disease such as multiple sclerosis largely rely on modulation of the immune system. Only limited treatment opt...

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Bibliographic Details
Main Authors: Simon M.G. Braun, Gregor-Alexander Pilz, Raquel A.C. Machado, Jonathan Moss, Burkhard Becher, Nicolas Toni, Sebastian Jessberger
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005501