Synergistic dual-modified liposome improves targeting and therapeutic efficacy of bone metastasis from breast cancer

Breast cancer frequently metastasizes to bone, where it leads to poor clinical prognosis. Due to the peculiarity of the bone microstructure, the uptake of drugs often happens at non-targeted sites, which produces a similar cytotoxicity in both cancerous and healthy cells. In this study, a rational s...

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Bibliographic Details
Main Authors: Xianzhu Ke, Wen Lin, Xiaokang Li, Hailiang Wang, Xin Xiao, Zheng Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2017.1396384