Comparison of methylation patterns generated from genomic and cell-line derived DNA using the Illumina Infinium MethylationEPIC BeadChip array

Comparison of methylation patterns generated from genomic and cell-line derived DNA using the Illumina Infinium MethylationEPIC BeadChip array

Abstract Objectives Genomic DNA (gDNA) is the optimal source of DNA for methylation analysis. This study compared methylation patterns in gDNA derived from blood with cell-line derived DNA (clDNA) from the same individuals. The clDNA had been generated via an Epstein-Barr virus transformation of the...

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Bibliographic Details
Main Authors: L. J. Smyth, J. Kilner, A. P. Maxwell, A. J. McKnight
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Research Notes
Subjects:
Cell-line
Diabetes
DNA
Epigenetics
Genomic
Methylation
Online Access:https://doi.org/10.1186/s13104-019-4853-4

Internet

https://doi.org/10.1186/s13104-019-4853-4

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