Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.

Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.

Parkinson disease (PD) is a complex neurodegenerative disorder with largely unknown genetic mechanisms. While the degeneration of dopaminergic neurons in PD mainly takes place in the substantia nigra pars compacta (SN) region, other brain areas, including the prefrontal cortex, develop Lewy bodies,...

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Bibliographic Details
Main Authors: Alexandra Dumitriu, Jeanne C Latourelle, Tiffany C Hadzi, Nathan Pankratz, Dan Garza, John P Miller, Jeffery M Vance, Tatiana Foroud, Thomas G Beach, Richard H Myers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-06-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22761592/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22761592/pdf/?tool=EBI

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