Lithium- Sensitive Store-Operated Ca2+ Entry in the Regulation of FGF23 Release

Lithium- Sensitive Store-Operated Ca2+ Entry in the Regulation of FGF23 Release

Background/Aims: Lithium, a widely used drug for the treatment of mood disorders, has previously been shown to stimulate the release of fibroblast growth factor FGF23, a powerful regulator of 1,25(OH)2D3 formation and mineral metabolism. The cellular mechanisms involved have remained elusive. Lithiu...

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Bibliographic Details
Main Authors: Bingbing Zhang, Jing Yan, Sebastian Schmidt, Madhuri S. Salker, Dorothea Alexander, Michael Föller, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-12-01
Series:Neurosignals
Subjects:
FGF23
Calcium
Orai1
STIM1
Lithium
SOCE
1,25(OH)2D3
2-APB
Online Access:http://www.karger.com/Article/FullText/442602

Internet

http://www.karger.com/Article/FullText/442602

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