A Lexicon of DNA Modifications: Their Roles in Embryo Development and the Germline

5-methylcytosine (5mC) on CpG dinucleotides has been viewed as the major epigenetic modification in eukaryotes for a long time. Apart from 5mC, additional DNA modifications have been discovered in eukaryotic genomes. Many of these modifications are thought to be solely associated with DNA damage. Ho...

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Bibliographic Details
Main Authors: Qifan Zhu, Reinhard Stöger, Ramiro Alberio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
5mC
6mA
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2018.00024/full