Therapeutic Renin Inhibition in Diabetic Nephropathy—A Review of the Physiological Evidence

Therapeutic Renin Inhibition in Diabetic Nephropathy—A Review of the Physiological Evidence

The purpose of this systematic review was to investigate the scientific evidence to support the use of direct renin inhibitors (DRIs) in diabetic nephropathy (DN). MEDLINE was searched for articles reported until 2018. A standardized dataset was extracted from articles describing the effects of DRIs...

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Bibliographic Details
Main Authors: Bianca Domingues Massolini, Stephanie San Gregorio Contieri, Giulia Severini Lazarini, Paula Antoun Bellacosa, Mirela Dobre, Georg Petroianu, Andrei Brateanu, Luciana Aparecida Campos, Ovidiu Constantin Baltatu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
diabetes mellitus
diabetic nephropathy
renin inhibitor
plasma renin activity
renin- angiotensin system
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00190/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.00190/full

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