miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS

miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS

Abstract Objective Onset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped‐MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small noncoding RNAs that affect gene expre...

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Main Authors: Brooke Rhead, Xiaorong Shao, Jennifer S. Graves, Tanuja Chitnis, Amy T. Waldman, Timothy Lotze, Teri Schreiner, Anita Belman, Lauren Krupp, Benjamin M. Greenberg, Bianca Weinstock–Guttman, Gregory Aaen, Jan M. Tillema, Moses Rodriguez, Janace Hart, Stacy Caillier, Jayne Ness, Yolanda Harris, Jennifer Rubin, Meghan S. Candee, Mark Gorman, Leslie Benson, Soe Mar, Ilana Kahn, John Rose, T. Charles Casper, Hong Quach, Diana Quach, Catherine Schaefer, Emmanuelle Waubant, Lisa F. Barcellos, the US Network of Pediatric MS Centers
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.786

Internet

https://doi.org/10.1002/acn3.786

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