Protein Arginine <i>N</i>-methyltransferases 5 and 7 Promote HIV-1 Production

Protein Arginine <i>N</i>-methyltransferases 5 and 7 Promote HIV-1 Production

Current therapies for human immunodeficiency virus type 1 (HIV-1) do not completely eliminate viral reservoirs in cells, such as macrophages. The HIV-1 accessory protein viral protein R (Vpr) promotes virus production in macrophages, and the maintenance of Vpr is essential for HIV-1 replication in t...

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Bibliographic Details
Main Authors: Hironobu Murakami, Takehiro Suzuki, Kiyoto Tsuchiya, Hiroyuki Gatanaga, Manabu Taura, Eriko Kudo, Seiji Okada, Masami Takei, Kazumichi Kuroda, Tatsuo Yamamoto, Kyoji Hagiwara, Naoshi Dohmae, Yoko Aida
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Viruses
Subjects:
hiv-1
vpr
prmt5
prmt7
vpr-binding protein
virus production
stability
macrophage
pathogenesis
Online Access:https://www.mdpi.com/1999-4915/12/3/355

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https://www.mdpi.com/1999-4915/12/3/355

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