Effect of ISM1 on the Immune Microenvironment and Epithelial-Mesenchymal Transition in Colorectal Cancer

Background: An increasing number of studies have shown that Isthmin 1 (ISM1), a secreted protein, is important in tumorigenesis and invasion, including in colorectal cancer (CRC). However, the mechanisms are still unclear. This study aims to explore the function and prognosis capacity of ISM1 in CRC...

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Bibliographic Details
Main Authors: Yuhui Wu, Xiaojing Liang, Junjie Ni, Rongjie Zhao, Shengpeng Shao, Si Lu, Weidong Han, Liangliang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.681240/full