Determination and Data Correlation of Solubility of Sofosbuvir Polymorphs in Ethyl Acetate + Toluene and Methyl <i>tert</i>-Butyl Ether Binary Solvents at the Temperature Range from 268.15 to 308.15 K

A gravimetric method was used to experimentally determine the (solid + liquid) equilibrium of sofosbuvir of crystalline forms A and B in both ethyl acetate + toluene and methyl <i>tert</i>-butyl ether (MTBE) + toluene binary solvents systems at atmosphere pressure. Experiments were carri...

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Bibliographic Details
Main Authors: Wei-Jie Ji, En-Fu Wang, Ming-Hui Qi
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/10/3/209