The Toll pathway underlies host sexual dimorphism in resistance to both Gram-negative and Gram-positive bacteria in mated Drosophila

The Toll pathway underlies host sexual dimorphism in resistance to both Gram-negative and Gram-positive bacteria in mated Drosophila

Abstract Background Host sexual dimorphism is being increasingly recognized to generate strong differences in the outcome of infectious disease, but the mechanisms underlying immunological differences between males and females remain poorly characterized. Here, we used Drosophila melanogaster to ass...

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Bibliographic Details
Main Authors: David F. Duneau, Hannah C. Kondolf, Joo Hyun Im, Gerardo A. Ortiz, Christopher Chow, Michael A. Fox, Ana T. Eugénio, J. Revah, Nicolas Buchon, Brian P. Lazzaro
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Biology
Subjects:
Sexual dimorphism
Innate immunity
Antimicrobial peptides
Drosophila melanogaster
Toll pathway
Online Access:http://link.springer.com/article/10.1186/s12915-017-0466-3

Internet

http://link.springer.com/article/10.1186/s12915-017-0466-3

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