Rationale for Therapeutic Silencing of Alpha-Synuclein in Parkinson’s Disease
The purpose of this paper is to provide the rationale for therapeutic silencing of the alpha-synuclein gene (SNCA) in Parkinson’s disease (PD). The paper reviews the public health significance of PD; the causal links between rare SNCA variants and familial PD; the association of common SNCA variants...
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| Format: | Article |
| Language: | English |
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Korean Movement Disorders Society
2011-05-01
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| Series: | Journal of Movement Disorders |
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| Online Access: | http://e-jmd.org/upload/jmd-4-1-1-1.pdf |