Betulin Complex in γ-Cyclodextrin Derivatives: Properties and Antineoplasic Activities in In Vitro and In Vivo Tumor Models

Betulin Complex in γ-Cyclodextrin Derivatives: Properties and Antineoplasic Activities in In Vitro and In Vivo Tumor Models

Given the present high incidence of melanoma and skin cancer, interest in potential drugs of plant origin has increased significantly. Pentacyclic lupane-type triterpenes are widely distributed in plants, offering numerous pharmacological benefits. Betulin is an important compound in the bark of Bet...

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Bibliographic Details
Main Authors: Florina Bojin, Rita Ambrus, Gerhard Wenz, Hai Ming Wang, Corina Danciu, Cristina Dehelean, Codruta Şoica, Mariana Anghel
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
betulin
cyclodextrin
MTT
immunocytochemistry
C57BL/6J mice
antitumor activity
Online Access:http://www.mdpi.com/1422-0067/13/11/14992

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http://www.mdpi.com/1422-0067/13/11/14992

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