Histone acetylation modifiers in the pathogenesis of Alzheimer’s disease

It is becoming more evident that histone acetylation, as one of the epigenetic modifications or markers, plays a key role in the etiology of Alzheimer’s disease (AD). Histone acetylases (HATs) and histone deacetylases (HDACs) are the well-known covalent enzymes that modify the reversible acetylation...

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Bibliographic Details
Main Authors: Xi eLu, Li eWang, Caijia eYu, Daohai eYu, Gang eYu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00226/full