In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis

In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis

Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into the nascent parasitophorous vacuole. These GRAs are belie...

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Bibliographic Details
Main Authors: Santhosh M. Nadipuram, Elliot W. Kim, Ajay A. Vashisht, Andrew H. Lin, Hannah N. Bell, Isabelle Coppens, James A. Wohlschlegel, Peter J. Bradley
Format: Article
Language:English
Published: American Society for Microbiology 2016-08-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/4/e00808-16

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http://mbio.asm.org/cgi/content/full/7/4/e00808-16

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