MiR-591 functions as tumor suppressor in breast cancer by targeting TCF4 and inhibits Hippo-YAP/TAZ signaling pathway

MiR-591 functions as tumor suppressor in breast cancer by targeting TCF4 and inhibits Hippo-YAP/TAZ signaling pathway

Abstract Background MicroRNAs have been involved in regulating crucial biological function in some tumors. However, the clinical role and functional effects of miR-591 in breast cancer remain unknown. Methods The expression of miR-591 was detected in breast cancer tissues and their paired normal tis...

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Bibliographic Details
Main Authors: Xin Huang, Fen Tang, Zeping Weng, Mengyao Zhou, Qing Zhang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Cancer Cell International
Subjects:
Breast cancer
MicroRNAs
miR-591
TCF4
YAP1
Online Access:http://link.springer.com/article/10.1186/s12935-019-0818-x

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http://link.springer.com/article/10.1186/s12935-019-0818-x

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