Angiopoietin-1 deficiency increases tumor metastasis in mice

Angiopoietin-1 deficiency increases tumor metastasis in mice

Abstract Background Angipoietin-1 activation of the tyrosine kinase receptor Tek expressed mainly on endothelial cells leads to survival and stabilization of endothelial cells. Studies have shown that Angiopoietin-1 counteracts permeability induced by a number of stimuli. Here, we test the hypothesi...

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Bibliographic Details
Main Authors: Iacovos P. Michael, Martina Orebrand, Marta Lima, Beatriz Pereira, Olga Volpert, Susan E. Quaggin, Marie Jeansson
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Cancer
Subjects:
Angiopoietin-1
Metastasis
MMTV-PyMT
B16F10 melanoma
Online Access:http://link.springer.com/article/10.1186/s12885-017-3531-y

Internet

http://link.springer.com/article/10.1186/s12885-017-3531-y

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