The vitamin D receptor inhibits the respiratory chain, contributing to the metabolic switch that is essential for cancer cell proliferation.

The vitamin D receptor inhibits the respiratory chain, contributing to the metabolic switch that is essential for cancer cell proliferation.

We recently described the mitochondrial localization and import of the vitamin D receptor (VDR) in actively proliferating HaCaT cells for the first time, but its role in the organelle remains unknown. Many metabolic intermediates that support cell growth are provided by the mitochondria; consequentl...

Full description

Bibliographic Details
Main Authors: Marco Consiglio, Michele Destefanis, Deborah Morena, Valentina Foglizzo, Mattia Forneris, Gianpiero Pescarmona, Francesca Silvagno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115816

Internet

https://doi.org/10.1371/journal.pone.0115816

Similar Items