Large-Scale Computational Discovery of Binding Motifs in tRNA Fragments

Accumulating evidence has suggested that tRNA-derived fragments (tRFs) could be loaded to Argonaute proteins and function as regulatory small RNAs. However, their mode of action remains largely unknown, and investigations of their binding mechanisms have been limited, revealing little more than micr...

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Bibliographic Details
Main Authors: Lingyu Guan, Vincent Lam, Andrey Grigoriev
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.647449/full