Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

Caveolae are plasma membrane invaginations containing cavin proteins that are disrupted upon stress stimuli, causing cavin release inside the cell. Here, McMahon et al. identify cavin interacting proteins using proteomic analyses and reveal functions in stress signaling that can promote apoptosis.

Bibliographic Details
Main Authors: Kerrie-Ann McMahon, Yeping Wu, Yann Gambin, Emma Sierecki, Vikas A. Tillu, Thomas Hall, Nick Martel, Satomi Okano, Shayli Varasteh Moradi, Jayde E. Ruelcke, Charles Ferguson, Alpha S. Yap, Kirill Alexandrov, Michelle M. Hill, Robert G. Parton
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11111-1

Internet

https://doi.org/10.1038/s41467-019-11111-1

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