Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma

Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma

Synovial sarcoma (SS) is an aggressive soft-tissue cancer with a poor prognosis and a propensity for local recurrence and distant metastasis. In this study, we investigated whether S phase kinase-associated protein (Skp2) plays an oncogenic role in tumor initiation, progression, and metastasis of SS...

Full description

Bibliographic Details
Main Authors: Jichuan Wang, Kenji Sato, Ed O'Donnell, Amit Singla, Simon Yaguare, Osama Aldahamsheh, Brian Batko, Hasibagan Borjihan, Janet Tingling, Jinghang Zhang, Daniel A. Weiser, David M. Loeb, Richard Gorlick, Edward L. Schwartz, Rui Yang, Xiaolin Zi, Hongling Zhao, David S. Geller, Bang H. Hoang
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320301431

Internet

http://www.sciencedirect.com/science/article/pii/S1936523320301431

Similar Items