Exploration of the mechanism by which icariin modulates hippocampal neurogenesis in a rat model of depression

Icariin (ICA) has a significant capacity to protect against depression and hippocampal injury, but it cannot effectively cross the blood-brain barrier and accumulate in the brain. Therefore, the mechanism by which ICA protects against hippocampal injury in depression remains unclear. In this study,...

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Bibliographic Details
Main Authors: Ning-Xi Zeng, Hui-Zhen Li, Han-Zhang Wang, Kai-Ge Liu, Xia-Yu Gong, Wu-Long Luo, Can Yan, Li-Li Wu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=3;spage=632;epage=642;aulast=Zeng