Intrathecal IgG Synthesis: A Resistant and Valuable Target for Future Multiple Sclerosis Treatments

Intrathecal IgG synthesis is a key biological feature of multiple sclerosis (MS). When acquired early, it persists over time. A growing body of evidence suggests that intrathecal Ig-secreting cells may be pathogenic either by a direct action of toxic IgG or by locally secreting bystander toxic produ...

Full description

Bibliographic Details
Main Author: Mickael Bonnan
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Multiple Sclerosis International
Online Access:http://dx.doi.org/10.1155/2015/296184