Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice

The interaction of SDF-1α (also known as CXCL12) with the CXCR4 receptor plays a critical role in the retention of hematopoietic stem cells (HSCs) in bone marrow. The viral macrophage inflammatory protein-II (vMIP-II), a human herpesvirus-8 (HHV-8)-encoded viral chemokine, can bind the CXCR4 recepto...

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Bibliographic Details
Main Authors: Yujia Mao, Qian Meng, Panpan Song, Siyu Zhu, Yan Xu, Evan Y. Snyder, Jing An, Ziwei Huang
Format: Article
Language:English
Published: SAGE Publishing 2018-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718784957