High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia

High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia

In this study, we extensively dissected the phenotypic complexity of the splenic tumor microenvironment (TME) in chronic lymphocytic leukemia (CLL) by high-dimensional mass cytometry (CyTOF). As a result, we identified potential new targets and tested a dual immune checkpoint blockade targeting the...

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Bibliographic Details
Main Authors: Marina Wierz, Bassam Janji, Guy Berchem, Etienne Moussay, Jerome Paggetti
Format: Article
Language:English
Published: Taylor & Francis Group 2018-08-01
Series:OncoImmunology
Subjects:
chronic lymphocytic leukemia
tumor microenvironment
immunotherapy
immune-checkpoint blockade
mass cytometry
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1465167

Internet

http://dx.doi.org/10.1080/2162402X.2018.1465167

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