Clinical significance of measuring plasminogen activator inhibitor-1 in sepsis

Abstract Background Disseminated thrombotic process in the microcirculation is considered to be an important cause of multiple organ dysfunction in sepsis. The fundamental purpose of this prothrombotic change was believed to be in the host defense against microbial dissemination. In that process, an...

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Bibliographic Details
Main Authors: Toshiaki Iba, Jecko Thachil
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Intensive Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40560-017-0250-z