Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons

Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons

Plexin-B2 deletion leads to aberrant lamination of cerebellar granule neurons (CGNs) and Purkinje cells. Although in the cerebellum Plexin-B2 is only expressed by proliferating CGN precursors in the outer external granule layer (oEGL), its function in CGN development is still elusive. Here, we used...

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Bibliographic Details
Main Authors: Eljo Van Battum, Celine Heitz-Marchaland, Yvrick Zagar, Stéphane Fouquet, Rohini Kuner, Alain Chédotal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
cerebellum
semaphorins
cell migration
cytokinesis
Online Access:https://elifesciences.org/articles/60554

Internet

https://elifesciences.org/articles/60554

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