Altered Antibody Response to Epstein-Barr Virus in Patients With Rheumatoid Arthritis and Healthy Subjects Predisposed to the Disease. A Twin Study

Altered Antibody Response to Epstein-Barr Virus in Patients With Rheumatoid Arthritis and Healthy Subjects Predisposed to the Disease. A Twin Study

Objectives: To study Epstein-Barr virus (EBV) antibody patterns in twin individuals with rheumatoid arthritis (RA) and their healthy co-twins, and to determine the heritability of antibody responses against the EBV encoded EBNA1 protein.Methods: Isotypes of EBNA1 antibodies were measured in 137 RA a...

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Bibliographic Details
Main Authors: Anders J. Svendsen, Marie Christine Wulff Westergaard, Anette Holck Draborg, René Holst, Kirsten O. Kyvik, Marianne A. Jakobsen, Peter Junker, Gunnar Houen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
Epstein Barr virus
EBNA1 isotypes
EBNA1 titer
predisposition
twin study
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.650713/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.650713/full

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