Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection

Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection

Abstract Background Fingolimod, a sphingosine-1-phosphate receptor modulator with well-described immunomodulatory properties involving peripheral immune cell trafficking, was the first oral agent approved for the treatment of relapsing remitting multiple sclerosis. Analogous immunomodulatory treatme...

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Bibliographic Details
Main Authors: Björn Ambrosius, Kalliopi Pitarokoili, Lisa Schrewe, Xiomara Pedreiturria, Jeremias Motte, Ralf Gold
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
Chronic inflammatory demyelinating neuropathy (CIDP)
Nerve conduction studies
Nerve excitability
Guillain-Barré syndrome (GBS)
Myelin
Online Access:http://link.springer.com/article/10.1186/s12974-017-0864-z

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http://link.springer.com/article/10.1186/s12974-017-0864-z

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